Ellen Pompeo On the Hardest Thing About ‘Grey’s Anatomy’ & Raising Kids in Hollywood

Ellen Pompeo reflects on the highs and lows of ‘Grey’s Anatomy’, the complexities of balancing motherhood with fame, and what lies ahead in her career. In this candid conversation, she shares what she loved—and struggled with—during her 19 seasons as Meredith Grey, how she’s only now watching the show with her children, and how she discovered acting after her working class Boston upbringing.

She speaks openly about the fleeting nature of celebrity, acknowledging, "If you believe that fame is real, or that fame is a thing, then you’re in trouble, because no one has it forever." She also looks back on her unlikely rise to becoming one of television’s highest-paid actresses, her teenage years as an “awkward” emo outsider, and the surreal experience of still being recognized at the grocery store.

Ellen revisits the harsh tabloid culture of the early 2000s, recalling the relentless scrutiny of her body. She appreciates how far celebrity culture has come, noting, "It was much, much more brutal 20 years ago." She also shares her thoughts on her latest project, a new series about Natalia Grace, and the lessons she’s learned over three decades in Hollywood. Ellen’s new show ‘Good American Family’ premieres March 19th on Hulu.

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Ellen Pompeo On the Hardest Thing About ‘Grey’s Anatomy’ & Raising Kids in Hollywood

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